Injectable platelet rich fibrin or (i-PRF) is a unique rejuvenation technique that uses the patient’s own blood plasma, enriched with;

– Platelets (a source of healing proteins and growth factors)

– Fibrin (the wound healing and regeneration matrix)

– Stem cells (the conductors of our body’s own healing and regeneration molecules)

This product is injected, resulting in activation of accelerated healing and regeneration. As a result, the body’s own powerful regenerative properties are concentrated and focused on the area of concern. iPRF intensifies the functioning and reproduction of cells, having a gentle, gradual, yet long lasting and accumulative effect.

Of course, i-PRF results are all the more impressive when incorporated into a treatment plan with hyaluronic acid fillers, wrinkle-relaxing treatments and other skin treatments. Producing virtually no downtime, this clinic-based treatment can also be used for skin and hair rejuvenation as treating problematic melasma and acne scars.

One of the newer applications of i-PRF is for the treatment of hair loss. It is used to reverse the hair loss in men and women as part of a multi-step scalp treatment that is done under local anaesthetic. It appears to ‘reset’ the hair follicles and reduce the impact of DHT (dihydrotestosterone) in those with Androgenetic Alopecia (pattern hair loss) and there is also growing evidence that PRP is the new ‘gold standard’ for Alopecia Areata.

What are the results?

General:

– New fibroblasts, collagen and elastin tissues are formed

– Skin elasticity and complexion is improved

– Pigmentation is reduced

Hair treatment:

– Hair regrowth

– Thicker hair

Based on a strong evidence, and thanks to Dr Joseph Choukroun; the inventor of iPRF technology, we are supporting the development of this technology to further assist our patients.

Is this the same as PRP? What is the difference between iPRF& PRP?

Both PRP (Platelet Rich Plasma) and PRF (Platelet Rich Fibrin) are platelet based growth factor treatments that are extracted using centrifuge. PRF is different from PRP in a way that there is no anticoagulant (blood thinner) added during the spin.

And here is the technical detail:

“The avoidance of clotting is physiological and is achieved through negative charge of the collecting tube to mimic the conditions within our own blood vessels (their lining is negatively charged) that prevent fibrin from creating a clot within them, thus, obtaining a platelet rich injectable fibrin. Once PRF is injected in the tissue, it transforms from liquid into a gel, which not only lead to filling of voids in folds and wrinkles but also provide a powerful regenerative matrix that releases platelets’ growth factors in a physiological controlled slow manner that enhances tissue regeneration in a better way than PRP.”

In addition, the enrichment of platelets in these two products is not the same. In PRP, the platelets are enriched two to four times above the physiological concentrations available in blood and there are very few circulating blood stem cells. In contrast, PRF contains all the platelets with no elimination of the powerful regenerative matrix (fibrin) in addition to another very rich source of growth factors and tissue regeneration: the circulating blood stem cells.

Why is fibrin important?

Dr Choukroun explains that Fibrin functions as a matrix that traps the platelets and controls their release of growth factors “very slowly and continuously over a time period of more than one week”. Growth factors’ release rate into the target tissue is important for tissue receptors to respond over a prolonged period of time following treatment.  “It’s not the amount of growth factors that’s the most important, but the rate it is released into the site. To treat severe infection, antibiotics can be injected drop by drop in an IV perfusion, ensuring that a stable concentration is maintained. This is the same in PRF biology—to obtain the most important function, a stable concentration must be maintained. The best is a drop-by-drop infusion”

Aesthetic Regenerative Use of PRF

Platelet growth factors in a fibrin scaffold are the first response to injury observed in all human tissue. Thus, the applications of PRF for healing and regeneration are not limited only to skin. Accelerated healing, new blood vessels and proliferation of cells producing collagen (fibroblasts) have been well demonstrated in biomedical research investigating the basic functions of these regenerative products. The vast clinical applications have been well documented in the literature by peer reviewed systematic reviews, we will discuss with how PRF could be used alone or in combination with other treatments to address your aesthetic regenerative concerns from skin rejuvenation to tissue regeneration.

iPRF Hair Growth Treatment

This is an all-natural non-surgical therapeutic option for patients who suffer from hair loss or thinning. iPRF can enhance the growth of hair follicles by stimulating the stem cells and other cells in the microenvironment of the hair follicle. These special Platelet cells promote healing and accelerate the rate and degree of tissue regeneration, resulting in new hair growth and thickening of existing hair.

It’s quite normal for everyone to shed some hair every day, but excessive hair loss is a big concern for both men and women. It can start with just a few hairs falling out, or shedding
when you comb your hair. Sometimes, this excess loss can progress to baldness. Baldness refers to excessive hair loss from your scalp, which can be either inherited or due to certain medications. Hair loss can also be a symptom of an underlying medical condition.
Men, women, and even children can experience hair loss.

Platelet-rich plasma (PRP), also known as autologous conditioned plasma, is a concentrate of platelet rich plasma protein derived from whole blood, centrifuged to remove red blood cells.

At CONQUER, we have been performing PRP/i-prf therapy as a proactive therapeutic option for hair loss in men and women. PRP is an exciting non-surgical therapeutic option for patients who require stimulation of hair growth for hair loss conditions. PRP was established 2 decades ago to be an effective medical treatment in the specialty fields of oral medicine, sports medicine and orthopedics. In hair restoration, evidence supports PRP therapy as a promising treatment option to promote hair growth. While PRP is in the early stages of scientific research, it is not meant to replace current FDA approved therapies such as DHT blockers (Propecia) and Minoxidil.

PRP guidelines for hair loss: 3 treatments in a span of 6-8 weeks! To maintain results, an additional treatment is recommended every 6-12 months. PRP is a non-surgical therapy in
hair loss treatment. There are many benefits of using PRP treatment to promote healing, for better hair growth. Highly concentrated growth factors in the form of platelets have been
shown to stimulate new hair growth, thicken the thinned out hair, and make hair
transplants grow thicker and healthier.

Procedure: First, approximately 60cc of blood iscollected from your vein. It’s very similar to having a routine blood test performed at your doctor’s clinic. The blood is collected and placed in a special container. The container is then placed in a machine called a centrifuge where your blood is spun for approximately 15 minutes. When the centrifuge has stopped spinning, your blood components have now been separated.
The concentrated platelets have been separated from your normal whole blood. The PRP that contains abundant growth factors is then injected into the scalp where hair thinning is present. There are no restrictions after the procedure.

PRP is a safe procedure without any side effects.